The interaction of actin filaments with microtubules and microtubule-associated proteins.

@article{Griffith1982TheIO,
  title={The interaction of actin filaments with microtubules and microtubule-associated proteins.},
  author={Lesa Griffith and Thomas D. Pollard},
  journal={The Journal of biological chemistry},
  year={1982},
  volume={257 15},
  pages={9143-51}
}
Purified actin and microtubule proteins polymerized together form a gel, while mixtures of actin with tubulin polymers lacking microtubule-associated proteins (MAPs) have low viscosities close to the sum of the viscosities of the constituents. Mixtures of actin and MAPs also have high viscosities. Our interpretation of these observations was that there is interaction of actin filaments and microtubules which is mediated by MAPs (Griffith, L. M., and Pollard, T. D. (1978) J. Cell Biol. 78, 958… CONTINUE READING