The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.

Abstract

The ets-family transcription factor ETV6 (TEL) has been shown to be the target of a large number of balanced chromosomal translocations in various hematological malignancies and in some soft tissue tumors. Furthermore, ETV6 is essential for hematopoietic stem cell function. We identified ETV6 interacting proteins using the yeast two hybrid system. One of… (More)

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