The interaction of BMP-7 and ActRII implicates a new mode of receptor assembly.

@article{Sebald2003TheIO,
  title={The interaction of BMP-7 and ActRII implicates a new mode of receptor assembly.},
  author={Walter Sebald and Thomas D Mueller},
  journal={Trends in biochemical sciences},
  year={2003},
  volume={28 10},
  pages={518-21}
}
The recently described structure of bone morphogenetic protein 7 in complex with the extracellular domain of the activin type receptor II provides a new and important paradigm to add to the list of possible modes of receptor assembly. A new mode of a ligand-mediated cooperative receptor assembly without receptor-receptor contacts yields new and exciting… CONTINUE READING