The interaction effects of binary mixtures of benzene and toluene on the developing heart of medaka (Oryzias latipes).

@article{Teuschler2005TheIE,
  title={The interaction effects of binary mixtures of benzene and toluene on the developing heart of medaka (Oryzias latipes).},
  author={Linda K. Teuschler and Chris Gennings and William Ralph Hartley and Hans Carter and Arunthavarani Thiyagarajah and Rita S Schoeny and Chris Cubbison},
  journal={Chemosphere},
  year={2005},
  volume={58 9},
  pages={1283-91}
}
The United States Environmental Protection Agency (USEPA) has pursued the estimation of risk of adverse health effects from exposure to chemical mixtures since the early 1980s. Methods used to calculate risk estimates of mixtures were often based on single chemical information that required assumptions of dose-addition or response-addition and did not consider possible changes in response due to interaction effects among chemicals. Full factorial designs for laboratory studies can produce… CONTINUE READING