The interaction between two TGF-β type I receptors plays important roles in ligand binding, SMAD activation, and gradient formation

Abstract

The goal of this report is to elucidate the contributions of the Drosophila TGF-beta type I receptors TKV and SAX to the activity gradient formed by the two BMP family members DPP and GBB that play important roles in growth and patterning of imaginal discs. Binding studies display preferential interactions of DPP and GBB with homodimers of TKV or SAX… (More)
DOI: 10.1016/j.mod.2010.04.001

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@article{Haerry2010TheIB, title={The interaction between two TGF-β type I receptors plays important roles in ligand binding, SMAD activation, and gradient formation}, author={Theodor E. Haerry}, journal={Mechanisms of Development}, year={2010}, volume={127}, pages={358-370} }