The interaction between prion protein and laminin modulates memory consolidation

@article{Coitinho2006TheIB,
  title={The interaction between prion protein and laminin modulates memory consolidation},
  author={A. Coitinho and A. R. Freitas and M. Lopes and G. Hajj and R. Roesler and R. Walz and J. Rossato and M. Cammarota and I. Izquierdo and V. Martins and R. Brentani},
  journal={European Journal of Neuroscience},
  year={2006},
  volume={24}
}
  • A. Coitinho, A. R. Freitas, +8 authors R. Brentani
  • Published 2006
  • Biology, Medicine
  • European Journal of Neuroscience
    • Cellular prion protein (PrPc) has a pivotal role in prion diseases. PrPc is a specific receptor for laminin (LN) γ1 peptide and several lines of evidence indicate that it is also involved in neural plasticity. Here we investigated whether the interaction between PrPc and LN plays a role in rat memory formation. We found that post‐training intrahippocampal infusion of PrPc‐derived peptides that contain the LN binding site ( and ) or of anti‐PrPc or anti‐LN antibodies that inhibit PrPc–LN… CONTINUE READING
    View on Wiley
    homepages.gac.edu
    70 Citations
    Background Citations
    31
    70 Citations
    Citation Type

    Citation Type

    Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminili γ1 chain
    • 88
    Short-term memory formation and long-term memory consolidation are enhanced by cellular prion association to stress-inducible protein 1
    • 77
    An ancient conserved role for prion protein in learning and memory
    • 8
    • PDF
    PrPC Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus
    • 37
    • PDF
    Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins
    • 82
    • PDF
    Laminin‐γ1 chain and stress inducible protein 1 synergistically mediate PrPC‐dependent axonal growth via Ca2+ mobilization in dorsal root ganglia neurons
    • 26
    Loss of STI1‐mediated neuronal survival and differentiation in disease‐associated mutations of prion protein
    • 3
    Prion protein and its ligand stress inducible protein 1 regulate astrocyte development
    • 60
    Insoluble cellular prion protein and its association with prion and Alzheimer diseases
    • 17
    Orchestrating Neurotrophic Activities 63 Prion Protein : Orchestrating Neurotrophic Activities
    • PDF

    References

    SHOWING 1-10 OF 71 REFERENCES
    Interaction of Cellular Prion and Stress-Inducible Protein 1 Promotes Neuritogenesis and Neuroprotection by Distinct Signaling Pathways
    • 242
    • PDF
    Cellular prion protein ablation impairs behavior as a function of age
    • 77
    Cellular prion protein binds laminin and mediates neuritogenesis.
    • 314
    Stress‐inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
    • 418
    Cellular prion protein transduces neuroprotective signals
    • 354
    • PDF
    Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival
    • 187
    Prion Protein Is Necessary for Latent Learning and Long-Term Memory Retention
    • 33
    Laminin‐induced PC‐12 cell differentiation is inhibited following laser inactivation of cellular prion protein
    • 112
    Prion protein induced signaling cascades in monocytes.
    • 47
    The biology of the cellular prion protein
    • 37