The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol

@article{Lee2014TheIB,
  title={The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol},
  author={Wan-Ru Lee and Tomonori Ishikawa and Michihisa Umetani},
  journal={Clinical Lipidology},
  year={2014},
  volume={9},
  pages={617 - 624}
}
Abstract Oxysterols are metabolites of cholesterol that are produced in liver and other peripheral tissues as a means to eliminate cholesterol to bile acid. Recent studies have revealed that the most abundant circulating oxysterol 27-hydroxycholesterol (27HC) is the first identified endogenous selective estrogen receptor modulator. 27HC levels correlate well with that of cholesterol, and also rise progressively with age. 27HC affects estrogen receptor function by the antagonism of estrogen… Expand
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TLDR
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TLDR
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TLDR
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