The interaction between bacteria and bile.

  title={The interaction between bacteria and bile.},
  author={M{\'a}ire Begley and Cormac G. M. Gahan and C. Ray Hill},
  journal={FEMS microbiology reviews},
  volume={29 4},
Commensal and pathogenic microorganisms must resist the deleterious actions of bile in order to survive in the human gastrointestinal tract. Herein we review the current knowledge on the mechanisms by which Gram-positive and Gram-negative bacteria contend with bile stress. We describe the antimicrobial actions of bile, assess the variations in bile tolerance between bacterial genera and examine the interplay between bile stress and other stresses. The molecular mechanisms underlying bile… CONTINUE READING
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