The integrins

@article{Takada2007TheI,
  title={The integrins},
  author={Yoshikazu Takada and Xiaojing Ye and Scott I Simon},
  journal={Genome Biology},
  year={2007},
  volume={8},
  pages={215 - 215}
}
The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands. They are transmembrane αβ heterodimers and at least 18 α and eight β subunits are known in humans, generating 24 heterodimers. Members of this family have been found in mammals, chicken and zebrafish, as well as lower eukaryotes, including sponges, the nematode Caenorhabditis elegans (two α and one β subunits, generating two integrins) and the fruitfly… CONTINUE READING
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