The integrin α v β 6 is critical for keratinocyte migration on both its known ligand , fibronectin , and on vitronectin

@inproceedings{Huang1998TheI,
  title={The integrin α v β 6 is critical for keratinocyte migration on both its known ligand , fibronectin , and on vitronectin},
  author={Xiaozhu Huang and Jian-Feng Wu and Suzanne M. Spong and Dean Sheppard},
  year={1998}
}
The integrin αvβ6 is expressed on a variety of epithelial cells during dynamic processes including organogenesis, tissue injury and malignant transformation. However, because of the lack of tools to specifically inhibit the function of this integrin, little is known about its effects on cell behavior. To directly examine the role of this integrin in cell migration, we used keratinocytes derived from wildtype mice or mice expressing a null mutation in the β6 subunit (β6−/−) to perform migration… CONTINUE READING