The integrated landscape of causal genes and pathways in schizophrenia

Abstract

Genome-wide association studies (GWAS) have identified more than 100 loci that show robust association with schizophrenia risk. However, due to the complexity of linkage disequilibrium and gene regulatory, it is challenging to pinpoint the causal genes at the risk loci and translate the genetic findings from GWAS into disease mechanism and clinical… (More)
DOI: 10.1038/s41398-018-0114-x

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