The integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function.

@article{Ho1998TheIM,
  title={The integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function.},
  author={Alexander Kon-I Ho and Gregory A. Raczniak and E B Ives and Susan R Wente},
  journal={Molecular biology of the cell},
  year={1998},
  volume={9 2},
  pages={
          355-73
        }
}
Integral membrane proteins are predicted to play key roles in the biogenesis and function of nuclear pore complexes (NPCs). Revealing how the transport apparatus is assembled will be critical for understanding the mechanism of nucleocytoplasmic transport. We observed that expression of the carboxyl-terminal 200 amino acids of the nucleoporin Nup116p had no effect on wild-type yeast cells, but it rendered the nup116 null strain inviable at all temperatures and coincidentally resulted in the… CONTINUE READING
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