The ins and outs of virulence gene expression: Mg2+ as a regulatory signal.

@article{Groisman1998TheIA,
  title={The ins and outs of virulence gene expression: Mg2+ as a regulatory signal.},
  author={Eduardo A. Groisman},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={1998},
  volume={20 1},
  pages={96-101}
}
The facultative intracellular pathogen Salmonella enterica serovar Typhimurium faces multiple environments during infection, including different cell types as well as extracellular fluids. We propose that Salmonella ascertains its cellular location by assessing the Mg2+ concentration of its milieu. A signal transduction system, PhoP/PhoQ, signals Salmonella… CONTINUE READING