The inner nuclear membrane protein LAP1 forms a native complex with B-type lamins and partitions with spindle-associated mitotic vesicles.

@article{Maison1997TheIN,
  title={The inner nuclear membrane protein LAP1 forms a native complex with B-type lamins and partitions with spindle-associated mitotic vesicles.},
  author={C Maison and A Pyrpasopoulou and Panayiotis Theodoropoulos and Spyros D. Georgatos},
  journal={The EMBO journal},
  year={1997},
  volume={16 16},
  pages={4839-50}
}
We have examined the in situ organization and nearest neighbours of the 'lamina-associated polypeptide-1' (LAP1), a type II membrane protein and a major constituent of the mammalian nuclear envelope. We show here that, during interphase, LAP1 forms multimeric assemblies which are suspended in the inner nuclear membrane and are specifically associated with B-type lamins. The LAP1-lamin B complex is distinct from analogous complexes formed by the 'lamina-associated polypeptide-2' (LAP2), another… CONTINUE READING

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Inner nuclear membraneIs associated anatomy of gene productLamin Type B
The inner nuclear membrane protein LAP1 forms a native complex with B - type lamins and partitions with spindle - associated mitotic vesicles .
We show here that , during interphase , LAP1 forms multimeric assemblies which are suspended in the inner nuclear membrane and are specifically associated with B - type lamins .
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