The innate immune response in ischemic acute kidney injury.

@article{Jang2009TheII,
  title={The innate immune response in ischemic acute kidney injury.},
  author={Hye Ryoun Jang and Hamid Rabb},
  journal={Clinical immunology},
  year={2009},
  volume={130 1},
  pages={41-50}
}
Kidney ischemia reperfusion injury is a major cause of morbidity in both allograft and native kidneys. Ischemia reperfusion-induced acute kidney injury is characterized by early, alloantigen-independent inflammation. Major components of the innate immune system are activated and participate in the pathogenesis of acute kidney injury, plus prime the allograft kidney for rejection. Soluble members of innate immunity implicated in acute kidney injury include the complement system, cytokines, and… CONTINUE READING
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