The inhibitory effects of terikalant on the contractile activity of galanin in isolated rat fundus strips.

@article{Korolkiewicz2000TheIE,
  title={The inhibitory effects of terikalant on the contractile activity of galanin in isolated rat fundus strips.},
  author={Roman Paweł Korolkiewicz and Zdzisław Konstański and Piotr Rekowski and Jarosław Ruczyński and Agnieszka Szyk and Renata Szczepańska and Jacek Petrusewicz},
  journal={Pharmacological research},
  year={2000},
  volume={41 5},
  pages={585-7}
}
The maximal responses (E(max)s) of isolated rat gastric fundus strips to 300 n m porcine galanin (Gal) were decreased in a concentration-dependent manner by terikalant (RP 62719). EC(50)of the agent equalled 4.39 microm (2.35-8.22). On the contrary the action of 30 n m of carbachol were not affected by the modulator in concentrations up to 30 microm. It is… CONTINUE READING