The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcγ receptor IIb on CD11c(+) dendritic cells in a murine model.

@article{Yamamoto2010TheIE,
  title={The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcγ receptor IIb on CD11c(+) dendritic cells in a murine model.},
  author={Maeri Yamamoto and Kenji Kobayashi and Yuriko Ishikawa and Kohei Nakata and Yasuhiro Funada and Yoshikazu Kotani and Atsuhiro Masuda and Toshiyuki Takai and Toshifumi Azuma and Mio Yoshida and Yoshihiro Nishimura},
  journal={Clinical and experimental immunology},
  year={2010},
  volume={162 2},
  pages={315-24}
}
Immunoglobulins (Igs) play important immunomodulatory effects on allergic asthma. Among these, IgG has been reported to regulate allergic inflammation in previous studies about immunotherapy and intravenous immunoglobulin therapy. In this study, to examine the immunomodulatory mechanisms of IgG and FcRs we evaluated the effects of intravenous (i.v.) rabbit IgG administration (IVIgG) on allergic airway inflammation and lung antigen-presenting cells (APCs) in a murine model of ovalbumin (OVA… CONTINUE READING

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