The inhibitory effect of strontium-doped calcium polyphosphate particles on cytokines from macrophages and osteoblasts leading to aseptic loosening in vitro.

@article{Huang2014TheIE,
  title={The inhibitory effect of strontium-doped calcium polyphosphate particles on cytokines from macrophages and osteoblasts leading to aseptic loosening in vitro.},
  author={Chengcheng Huang and Li Li and Xixun Yu and Zhipeng Gu and Xu Zhang},
  journal={Biomedical materials},
  year={2014},
  volume={9 2},
  pages={
          025010
        }
}
Aseptic loosening is a common cause of joint implant failure in humans. In order to enhance implant stability, we need to develop a new material that not only promotes the wear resistance of components of an artificial joint, but also possesses the pharmaceutical efficacy of protecting patients against aseptic loosening. Strontium-doped calcium polyphosphate (SCPP) has been found to have this potential ability. The goal of this study is to respectively quantify the levels of TNF-α (for… CONTINUE READING
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