The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells

Abstract

D-Glucosamine markedly inhibits thymidine incorporation into the TCA-insoluble fraction and thymidine kinase activity in HeLa cells. Both the inhibitory effects are also observed in isolated retinas of chick embryos. In this case the inhibitory effects are age-dependent and the magnitude of the responses decreases with embryonic development. In addition the time of exposure to D-glucosamine which is necessary to reveal the inhibitory effect on thymidine kinase increases with the age of the embryos.

DOI: 10.1007/BF01949733

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Cite this paper

@article{Tesoriere1984TheIE, title={The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells}, author={Giovanni Tesoriere and Luisa Tesoriere and Renza Vento and Michela Giuliano and Gianluca Cantoro}, journal={Experientia}, year={1984}, volume={40}, pages={705-707} }