The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein.

Abstract

The plutonium (plu) gene product controls DNA replication early in Drosophila development. plu mutant females lay unfertilized eggs that have undergone extensive DNA synthesis. In fertilized embryos from plu mutant mothers, S-phase is uncoupled from mitosis. The gene is expressed only in ovaries and embryos, null alleles are strict maternal effect mutations… (More)

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Cite this paper

@article{Axton1994TheIO, title={The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein.}, author={J. Myles Axton and Fay L Shamanski and L. M. Young and D. S. Henderson and Jeanette Boyd and Terry L Orr-Weaver}, journal={The EMBO journal}, year={1994}, volume={13 2}, pages={462-70} }