The inhibition of the apoptosis pathway by the Coxiella burnetii effector protein CaeA requires the EK repetition motif, but is independent of survivin.

@article{Bisle2016TheIO,
  title={The inhibition of the apoptosis pathway by the Coxiella burnetii effector protein CaeA requires the EK repetition motif, but is independent of survivin.},
  author={Stephanie Bisle and Leonie Klingenbeck and V{\'i}tor Borges and Katharina Sobotta and Jan Schulze-Luehrmann and Christian Menge and Carsten Heydel and Joao Paulo da Silva Gomes and Anja Luehrmann},
  journal={Virulence},
  year={2016},
  volume={7 4},
  pages={400-12}
}
ABSRTACT Coxiella burnetii is an obligate intracellular bacterium that causes Query (Q) fever, a zoonotic disease. It requires a functional type IV secretion system (T4SS) which translocate bacterial effector proteins into the host cell cytoplasm and thereby facilitates bacterial replication. To date, more than 130 effector proteins have been identified, but their functions remain largely unknown. Recently, we demonstrated that one of these proteins, CaeA (CBU1524) localized to the host cell… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS