The inherited leukodystrophies: A clinical overview

@article{Aicardi1993TheIL,
  title={The inherited leukodystrophies: A clinical overview},
  author={J. P. Aicardi},
  journal={Journal of Inherited Metabolic Disease},
  year={1993},
  volume={16},
  pages={733-743}
}
The leukodystrophies are degenerative diseases that involve primarily the white matter of the brain. The most common leukodystrophies result from known disturbances in the synthesis or catabolism of myelin such as a block in the catabolism of sulphatides and of galactocerebrosides, respectively, in metachromatic leukodystrophy and in Krabbe disease, or from synthesis of an abnormal proteolipid protein in Pelizaeus-Merzbacher disease. The cause of white matter involvement in other… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Peroxisomal disease

  • HW Moser
  • Adv Pediatr
  • 1989
Highly Influential
3 Excerpts

Diseases of the Nervous System in Childhood

  • J Aicardi
  • 1992
1 Excerpt

Early treated phenylketonuria: do MR images parallel clinical, biochemical and neurophysiological data

  • UK Meyding-Lamade, J Pietz, G Fahrendorf, KJ Sartor
  • J Neurol
  • 1992

X-linked inherited demyelinating disease (Pelizaeus-Merzbacher disease); tight linkage with the proteolipoprotein gene (PLP) in 17 families

  • O Boespflug-Tanguy, A Cavagna, C Mimault
  • J NeuroI 239
  • 1992

Similar Papers

Loading similar papers…