The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype

@article{KleinWieringa2011TheIF,
  title={The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype},
  author={Inge R. Klein-Wieringa and Margreet Kloppenburg and Yvonne M. Bastiaansen-Jenniskens and E. Yusuf and Joanneke C Kwekkeboom and Hanane el-Bannoudi and Rob G. H. H. Nelissen and A Zuurmond and Vedrana Stojanovic-Susulic and Gerjo J.V.M. van Osch and Ren{\'e} E M Toes and Andreea Ioan-Facsinay},
  journal={Annals of the Rheumatic Diseases},
  year={2011},
  volume={70},
  pages={851 - 857}
}
  • Inge R. Klein-Wieringa, Margreet Kloppenburg, +9 authors Andreea Ioan-Facsinay
  • Published 2011
  • Medicine
  • Annals of the Rheumatic Diseases
  • Objectives Obesity is a risk factor for the development of osteoarthritis (OA) in hands and knees. Adipose tissue can secrete different adipokines with powerful immunomodulatory effects. The infrapatellar fat pad (IFP) is an intra-articular organ in the vicinity of the synovium and cartilage. It is hypothesised that IFP-derived soluble factors could contribute to pathological processes in the knee joint. A study was therefore undertaken to compare the release of inflammatory mediators in the… CONTINUE READING

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