Is the inframammary fold an anatomical entity? In order to answer this question, the authors conducted an anatomical, histological and radiological study. The results of these studies were concordant and were able to anatomically define the inframammary fold. The inframammary fold corresponds to a division of the fascia superficialis. It contains numerous fibres stretched between the fascia superficialis and the fascia prepectoralis. In contrast, there are no fibres connecting the fascia superficialis to the deep dermis.