The information efficacy of a synapse

  title={The information efficacy of a synapse},
  author={Michael London and Adi Schreibman and Michael H{\"a}usser and Matthew Evan Larkum and Idan Segev},
  journal={Nature Neuroscience},
We provide a functional measure, the synaptic information efficacy (SIE), to assess the impact of synaptic input on spike output. SIE is the mutual information shared by the presynaptic input and postsynaptic output spike trains. To estimate SIE we used a method based on compression algorithms. This method detects the effect of a single synaptic input on the postsynaptic spike output in the presence of massive background synaptic activity in neuron models of progressively increasing realism… CONTINUE READING