The influence of topical capsaicin on the local thermal control of skin blood flow in humans.

@article{Stephens2001TheIO,
  title={The influence of topical capsaicin on the local thermal control of skin blood flow in humans.},
  author={Dan P. Stephens and Nisha Charkoudian and Jenny Benevento and James Mark Johnson and Jean Louis Saumet},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2001},
  volume={281 3},
  pages={
          R894-901
        }
}
To test whether heat-sensitive receptors participate in the cutaneous vascular responses to direct heating, we monitored skin blood flow (SkBF; laser Doppler flowmetry) where the sensation of heat was induced either by local warming (T(Loc); Peltier cooling/heating unit) or by both direct warming and chemical stimulation of heat-sensitive nociceptors (capsaicin). In part I, topical capsaicin (0.075 or 0.025%) was applied to 12 cm(2) of skin 1 h before stepwise local warming of untreated and… CONTINUE READING

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