The influence of the structural characteristics of the substrate and the medium on the stability of triflusal and acetylsalicylic acid in micellar systems

@inproceedings{Ferrit2008TheIO,
  title={The influence of the structural characteristics of the substrate and the medium on the stability of triflusal and acetylsalicylic acid in micellar systems},
  author={M. Ferrit and Carlos E. del Valle and Fernando Mart{\'i}nez Mart{\'i}nez},
  year={2008}
}
Abstract A spectrophotometric study of the alkaline hydrolysis of two salicylic acid (SA) derived drugs, performed on acetylsalicylic acid (ASA) and triflusal, both in the absence and presence of cationic micelles. In the absence of micelles, a catalytic effect is produced by the favoured OH− ion in the molecule of triflusal, due to the presence of the trifluoromethyl group. The surfactants used were: hexadecyltrimethylammonium hydroxide (HDTAOH), hexadecyltrimethylammonium chloride (HDTACl… CONTINUE READING

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