The influence of the BCL11A polymorphism on the phenotype of patients with beta thalassemia could be affected by the beta globin locus control region and/or the Xmn1-HBG2 genotypic background.

@article{Neishabury2013TheIO,
  title={The influence of the BCL11A polymorphism on the phenotype of patients with beta thalassemia could be affected by the beta globin locus control region and/or the Xmn1-HBG2 genotypic background.},
  author={Maryam Neishabury and Fahimeh Zamani and Elahe Keyhani and Azita Azarkeivan and Seyedeh Sedigheh Abedini and Masumeh Sadat Eslami and Setareh Talebi Kakroodi and Mahjoobeh Jafari Vesiehsari and Hossein Najmabadi},
  journal={Blood cells, molecules & diseases},
  year={2013},
  volume={51 2},
  pages={80-4}
}
To study the influence of the β globin locus control region (LCR) genotypic background on the phenotype modifying role of BCL11A polymorphisms, 100 cases of thalassemia, 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms (rs11886868 and rs766432) in the intronic region of this gene. The effect of these polymorphisms on HbF variation was also examined in 122 normal… CONTINUE READING

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To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
To study the influence of the β globin locus control region ( LCR ) genotypic background on the phenotype modifying role of BCL11A polymorphisms , 100 cases of thalassemia , 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms ( rs11886868 and rs766432 ) in the intronic region of this gene .
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