The influence of spray properties on intranasal deposition.

@article{Foo2007TheIO,
  title={The influence of spray properties on intranasal deposition.},
  author={Mow Yee Foo and Yung-sung Cheng and Wei-chung Su and Maureen D. Donovan},
  journal={Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine},
  year={2007},
  volume={20 4},
  pages={
          495-508
        }
}
While numerous devices, formulations, and spray characteristics have been shown to influence nasal deposition efficiency, few studies have attempted to identify which of these interacting factors plays the greatest role in nasal spray deposition. The deposition patterns of solutions with a wide range of surface tensions and viscosities were measured using an MRI-derived nasal cavity replica. The resulting spray plumes had angles between 29 degrees and 80 degrees and contained droplet sizes (D… CONTINUE READING

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