The influence of sodium ion binding on factor IXa activity.

@article{Gopalakrishna2006TheIO,
  title={The influence of sodium ion binding on factor IXa activity.},
  author={Kota Gopalakrishna and Alireza R Rezaie},
  journal={Thrombosis and haemostasis},
  year={2006},
  volume={95 6},
  pages={
          936-41
        }
}
Sodium plays an important role in modulating both the amidolytic and proteolytic activities of thrombin. By contrast, while the optimal amidolytic activity of factor Xa requires Na(+), the proteolytic activity of factor Xa in the prothrombinase complex is minimally affected by the monovalent cation. In this study, we analyzed the effect of Na(+) on the amidolytic and proteolytic activity of factor IXa in the absence and presence of factor VIIIa. Factor IXa exhibited normal activity towards a… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Similar Papers

Loading similar papers…