The influence of sex and of testosterone upon fatty liver due to ethionine.

  title={The influence of sex and of testosterone upon fatty liver due to ethionine.},
  author={E. Farber and D. Koch-Weser and H. Popper},
  volume={48 2},
  • E. Farber, D. Koch-Weser, H. Popper
  • Published 1951
  • Biology, Medicine
  • Endocrinology
  • ETHIONINE (α-amino-γ-ethylmercapto-butyric acid), a presumed antagonist of methionine, had previously been shown to induce a fatty infiltration of the liver in fasted female rats (Farber, Simpson and Tarver, 1950). Methionine prevented the rise in liver lipids and protected the animals against death while other amino acids, as well as choline, inositol and dimethylthetin were ineffective. Glucose, in large doses, also prevented and cured the fatty change, but failed to prevent the death of the… CONTINUE READING
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