The influence of selective serotonin reuptake inhibitors on human platelet serotonin.

@article{MaurerSpurej2004TheIO,
  title={The influence of selective serotonin reuptake inhibitors on human platelet serotonin.},
  author={Elisabeth Maurer-Spurej and Cheryl Pittendreigh and Kevin Solomons},
  journal={Thrombosis and haemostasis},
  year={2004},
  volume={91 1},
  pages={119-28}
}
Clinical depression has been proposed to be an independent risk factor for cardiovascular disease. While it is suggested that selective serotonin reuptake inhibitors (SSRIs) reduce the risk of acute cardiovascular problems of depressed patients, the effect of SSRIs on platelets, the only blood cells committed to serotonin (5-HT) transport, remains largely unknown. The goal of this pilot study was to measure the 5-HT levels in platelets of untreated and SSRI-treated depressed patients and normal… CONTINUE READING

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