The influence of prostaglandins E1 and E2 on ouabain cardiotoxicity in the cat.


The capacity of prostaglandins E1 (PGE1) and E2 (PGE2) to influence the lethal dose and lethal myocardial content of ouabain was studied in intact cats and cats whose spinal cords had been transected. The administration of PGE1 and PGE2 to intact cats was associated with an increase in lethal dose and ventricular content of ouabain. Spinal cord transection… (More)


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