The influence of prostaglandin E2 and oxytocin on the incorporation of [3H]proline and [3H]glucosamine in the human amnion.

  title={The influence of prostaglandin E2 and oxytocin on the incorporation of [3H]proline and [3H]glucosamine in the human amnion.},
  author={Jostein Tjugum and Anders Norstr{\"o}m},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  volume={19 3},
  • J. Tjugum, A. Norström
  • Published 1 March 1985
  • Medicine
  • European journal of obstetrics, gynecology, and reproductive biology
Fetal membranes were obtained in connection with 1st-trimester abortion and vaginal delivery or elective caesarean section at term. Pieces of the isolated amnion membrane were incubated in vitro with [3H]proline or [3H]glucosamine in the presence of prostaglandin (PG) E2 or oxytocin. PGE2 reduced the labelling with [3H]proline in the 1st trimester and in membranes obtained at vaginal delivery, whereas an increase of incorporation was observed before start of labour. Oxytocin reduced [3H]proline… 
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