The influence of prostaglandin E2 and oxytocin on the incorporation of [3H]proline and [3H]glucosamine in the human amnion.

@article{Tjugum1985TheIO,
  title={The influence of prostaglandin E2 and oxytocin on the incorporation of [3H]proline and [3H]glucosamine in the human amnion.},
  author={Jostein Tjugum and Anders Norstr{\"o}m},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  year={1985},
  volume={19 3},
  pages={
          137-43
        }
}
  • J. Tjugum, A. Norström
  • Published 1 March 1985
  • Medicine
  • European journal of obstetrics, gynecology, and reproductive biology
Fetal membranes were obtained in connection with 1st-trimester abortion and vaginal delivery or elective caesarean section at term. Pieces of the isolated amnion membrane were incubated in vitro with [3H]proline or [3H]glucosamine in the presence of prostaglandin (PG) E2 or oxytocin. PGE2 reduced the labelling with [3H]proline in the 1st trimester and in membranes obtained at vaginal delivery, whereas an increase of incorporation was observed before start of labour. Oxytocin reduced [3H]proline… Expand
9 Citations
A prospective double blind study comparing the effects of oxytocin and human chorionic gonadotrophin as trigger for ovulation
TLDR
Oxytocin was found to be a viable alternative to hCG for triggering ovulation in infertile patients and failed to reach statistical difference in the oxytocin group compared with the hCG group. Expand
Activin A is stimulated by tumor necrosis factor-alpha and modulates collagen gene expression in human amniotic cells
TLDR
The idea that activin A is involved in the pathophysiology of amnionitis is supported by evidence that accumulating evidence supports the idea of activation A as a modulator of inflammation. Expand
Premature rupture of the fetal membranes.
The membranes surrounding the amniotic cavity are composed of the amnion and the chorion, which are closely adherent layers consisting of several cell types, including epithelial cells, mesenchymalExpand
MICROBIOLOGICAL PATTERN IN CASES OF PRETERM PREMATURE RUPTURE OF FETAL MEMBRANES (PPROM): A CASE-CONTROL STUDY SUBMITTED BY: DR. OLUWAFEMI ADEBISI ADEWUMI
  • 2017
BACKGROUND: Preterm premature rupture of fetal membranes (PPROM) is a significant contributor to adverse obstetric outcome. The need for a continuous search for the aetiological factors to enable itsExpand
Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis.
TLDR
Uterine wall thickness measurement in second trimester can help to identify preterm delivery in pregnant women with adenomyosis. Expand
Adenomyosis as a Potential Risk Factor for Adverse Pregnancy Outcomes: A Multicenter Case-Control Study.
TLDR
Women with diffuse adenomyosis require more careful perinatal management than previously thought and are significantly more likely to experience preterm labor, cesarean delivery, and postpartum hemorrhage. Expand
Chorioamniotic membrane separation following fetal myelomeningocele repair: incidence, risk factors and impact on perinatal outcome
  • R. Corroenne, M. Yepez, +7 authors M. Sanz Cortes
  • Medicine
  • Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 2019
TLDR
This study evaluated the incidence of CAS after prenatal MMC repair, to determine risk factors associated with its occurrence, and to assess its association with adverse perinatal outcomes. Expand
Adverse pregnancy outcomes associated with adenomyosis with uterine enlargement
The aim of this study was to elucidate the risk of poor pregnancy outcomes in women with adenomyosis by comparing their outcomes to those of women without uterine abnormalities.
Adenomyosis and risk of preterm delivery
TLDR
The objective is to evaluate the risk of preterm delivery in patients with adenomyosis and to establish a protocol for evaluating this risk in the event of a pregnancy. Expand

References

SHOWING 1-10 OF 17 REFERENCES
Influence of prostaglandin E2 on the biosynthesis of connective tissue constituents in the pregnant human cervix
Abstract Uterine cervical tissue was obtained from pregnant women undergoing abortion of caesarean section. The tissue was incubated in Krebs-Ringer bicarbonate buffer containing prostaglandin (PG)Expand
Effects of oxytocin on cervical and uterine connective tissue.
TLDR
The results suggest that oxytocin under in vitro experimental conditions influences cervical connective tissue metabolism which is in contrast to current clinical experiences. Expand
Influence of prostaglandin E2 on proteoglycan synthesis in the human ovarian follicle wall.
TLDR
The demonstrated increase in the incorporation of 3H-glucosamine in the apical wall of the mature follicle in response to PGE2 indicates that PG-mediated stimulation of proteoglycan synthesis is of importance for follicular rupture. Expand
The regulatory influence of prostaglandins on protein synthesis in the human non pregnant cervix.
TLDR
The present data point to an acute effect of PGE2 and PGF2 alpha on cervical collagen metabolism and indicate furthermore that the process is steroid hormone dependent. Expand
Collagen synthesis inhibition by PGE2 within the human follicular wall--one possible mechanism underlying ovulation.
TLDR
It is suggested that the registered biochemical changes induced by PGE2 are of importance for the process of human ovulation. Expand
Collagen Content of Human Amniotic Membranes: Effect of Gestation Length and Premature Rupture
TLDR
The changes inAmnion collagen during gestation and the differences observed with PROM suggest that weakening of the amnion in preparation for rupture may be determined partly by factors controlling the synthesis and degradation of collagen. Expand
Oxytocin receptors and human parturition: a dual role for oxytocin in the initiation of labor
TLDR
In vitro, prostaglandin production by the decidua, but not by the myometrium, was increased by the addition of oxytocin, and Oxytocin may stimulate uterine contractions by acting both directly on theMyometrium and indirectly on decidual prostaglandsin production. Expand
Changes in the physical properties and in the collagen and hexosamine contents of the foetal membranes during pregnancy in the rat
TLDR
The strength of the membranes is tested by measuring the pressure required to rupture a portion held across a standard, circular aperture, and results suggest an increase in the polysaccharide component of the connective tissues. Expand
Interrelationships of mucopolysaccharide and collagen in connective tissue remodelling.
  • M. Flint
  • Biology, Medicine
  • Journal of embryology and experimental morphology
  • 1972
TLDR
During this study it was found that the Masson9s trichrome stain appears to be a precise indicator of the state of tension of collagen fibres within the tendon, and other connective tissues. Expand
The interaction of collagen and acid mucopolysaccharides. A model for connective tissue.
  • M. Mathews
  • Chemistry, Medicine
  • The Biochemical journal
  • 1965
TLDR
A schematic model for the interaction of collagen and chondroitin sulphate-protein macromolecules shows parallel-ordered interaction ofcollagen fibrils withChondroit in sulphate side chains of the chond Detroitin sulphATE-proteinmacromolecule, which appears mainly dependent on electrostatic forces and is increased with increase in chain length of the polysaccharide. Expand
...
1
2
...