The influence of progesterone on the antidiuretic and oxytocic activities of the posterior pituitary lobe of female rats

@article{Piechowiak1976TheIO,
  title={The influence of progesterone on the antidiuretic and oxytocic activities of the posterior pituitary lobe of female rats},
  author={H. Piechowiak and U. Jantzen and August Koenig},
  journal={Archiv f{\"u}r Gyn{\"a}kologie},
  year={1976},
  volume={221},
  pages={139-144}
}
Mature, female rats received 2 mg progesterone i.m. during proestrus and estrus and 4 mg during all stages of the sexual cycle. 24 h after injection the animals were decapitated. Antidiuretic and oxytocic activities of the posterior pituitary lobe were tested by bioassay. The increased hormone content of the neurohypophysis in reaction to progesterone administration is explained by an inhibiting effect of progesterone on hormone secretion. The physiological and possible pathophysiological… CONTINUE READING