The influence of placental malaria infection and maternal hypergammaglobulinemia on transplacental transfer of antibodies and IgG subclasses in a rural West African population.

@article{Okoko2001TheIO,
  title={The influence of placental malaria infection and maternal hypergammaglobulinemia on transplacental transfer of antibodies and IgG subclasses in a rural West African population.},
  author={Brown Jacob Okoko and L H Wesumperuma and Martin O C Ota and Margaret Pinder and Winston A S Banya and Samuel G{\'o}mez and K W Mcadam and Anne C Hart},
  journal={The Journal of infectious diseases},
  year={2001},
  volume={184 5},
  pages={627-32}
}
Two hundred thirteen mother-baby pairs in The Gambia were studied to determine the influence of placental malaria infection and maternal hypergammaglobulinemia on transplacental antibody transfer. Antibody transfer for herpes simplex virus 1 (HSV-1), respiratory syncytial virus (RSV), and varicella-zoster virus (VZV) was significantly reduced by placental malaria infection by 69%, 58%, and 55%, respectively. Maternal hypergammaglobulinemia was associated with a significant reduction in antibody… CONTINUE READING

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