The influence of pH on the convertogenic activity of plant phenolics.

@article{Rosin1984TheIO,
  title={The influence of pH on the convertogenic activity of plant phenolics.},
  author={Miriam Pearl Rosin},
  journal={Mutation research},
  year={1984},
  volume={135 2},
  pages={109-13}
}
The genotoxicity of plant phenolics, including pyrogallol, gallic acid, resorcinol and catechin, and a water extract and tannin fraction of betel nut (Areca catechu) was examined at pH levels ranging from 5 to 10. Strain D7 of Saccharomyces cerevisiae was used since the cells can withstand a wide range of pH levels without any loss of viability. At alkaline pH ranges, the examined phenolics and betel nut extracts induced mitotic conversion, whereas they lacked this capacity at acid pH levels… CONTINUE READING