The influence of ovariectomy and estrogen replacement on voiding patterns and detrusor muscarinic receptor affinity in the rat.

Abstract

A rat model of ovariectomy-induced voiding dysfunction was established and the effects of ovariectomy and subsequent estrogen replacement on the affinity of muscarinic receptors in the rat bladder were determined. Voiding frequency and spatial distribution patterns were documented in sham-operated (control), and ovariectomized (placebo- or estrogen-treated… (More)

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@article{Liang2002TheIO, title={The influence of ovariectomy and estrogen replacement on voiding patterns and detrusor muscarinic receptor affinity in the rat.}, author={Willmann Liang and Karoush Afshar and Lynn Stothers and Ismail Laher}, journal={Life sciences}, year={2002}, volume={71 3}, pages={351-62} }