The influence of octreotide treatment on pulsatile growth hormone release in acromegaly.

@article{Roelfsema1990TheIO,
  title={The influence of octreotide treatment on pulsatile growth hormone release in acromegaly.},
  author={Ferdinand Roelfsema and Hans de Boer and Marijke Fr{\"o}lich},
  journal={Clinical endocrinology},
  year={1990},
  volume={33 2},
  pages={297-306}
}
The pulsatile release of GH was investigated in eight active acromegalic patients before and during a subcutaneous infusion of 300 micrograms octreotide/24 h for 4 weeks. The number of GH pulses increased from a basal value of 14.4/24h to 16.3/24h during octreotide therapy. At the same time the mean GH concentration, valley concentration, peak height and… CONTINUE READING