The influence of obstructive sleep apnea on the expression of glycerol-3-phosphate dehydrogenase1 gene

  title={The influence of obstructive sleep apnea on the expression of glycerol-3-phosphate dehydrogenase1 gene},
  author={Camila Guindalini and Kil Seong Lee and Monica Levy Andersen and Rog{\'e}rio Santos-Silva and Lia Bittencourt and S{\'e}rgio Tufik},
  journal={Experimental Biology and Medicine},
  pages={52 - 56}
Glycerol-3-phosphate dehydrogenase1 (GPD1) is considered to be a key enzyme that connects carbohydrate and lipid metabolism. This gene is induced in response to sleep deprivation, suggesting a potential role for this enzyme in the manifestation of obstructive sleep apnea (OSA). This study aims to examine the effects of sleep apnea, obesity and other relevant clinical parameters on GPD1 expression in the peripheral blood of a rigorously selected sample population in order to identify a… 
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  • E. Tasali, M. Ip
  • Medicine
    Proceedings of the American Thoracic Society
  • 2008
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