The influence of nifedipine and diltiazem on serum theophylline concentration-time profiles.

Abstract

Chronic dosing studies in normal volunteers have shown that both nifedipine and diltiazem exert a small effect on serum theophylline concentrations, which tend to be higher during concurrent nifedipine therapy. The differences were not significant but may be of clinical interest as theophylline causes adverse effects at higher plasma concentrations.

Cite this paper

@article{Smith1989TheIO, title={The influence of nifedipine and diltiazem on serum theophylline concentration-time profiles.}, author={Steve Smith and C A Haffner and Martin J Kendall}, journal={Journal of clinical pharmacy and therapeutics}, year={1989}, volume={14 5}, pages={403-8} }