The influence of naloxone on dental pain threshold elevation produced by peripheral conditioning stimulation at high frequency.

@article{Pertovaara1981TheIO,
  title={The influence of naloxone on dental pain threshold elevation produced by peripheral conditioning stimulation at high frequency.},
  author={Antti Pertovaara and Pentti Kemppainen},
  journal={Brain research},
  year={1981},
  volume={215 1-2},
  pages={426-9}
}
The phasic dental pain threshold elevation produced by high-frequency transcutaneous electrical nerve stimulation (TENS) in healthy humans was not abolished by naloxone. A prolonged (20 min) high-frequency TENS did not cause any tonic pain threshold elevation. The results indicate that opioid-dependent systems have only a minor if any contribution to alleviation of experimental pain during high-frequency TENS.