The influence of mast cell mediators on migration of SW756 cervical carcinoma cells.

@article{Rudolph2008TheIO,
  title={The influence of mast cell mediators on migration of SW756 cervical carcinoma cells.},
  author={Maria Isolde Rudolph and Yadira V Boza and Roger Yefi and Sandra Luza and Edilia Andrews and Alicia Beatriz Penissi and Pablo Garrido and Isolde Gina Rojas},
  journal={Journal of pharmacological sciences},
  year={2008},
  volume={106 2},
  pages={208-18}
}
The role of mast cell mediators on cervical cancer cell migration was assessed using an in vitro assay of scratch wound healing onto monolayers of HPV18-positive cervical carcinoma cells (SW756). Migration of SW756 cells was accelerated by co-culture with the mast cell line LAD2. This effect was inhibited by the H1R antagonist pyrilamine and the cannabinoid agonists 2-arachidonylglycerol (2AG) and Win 55,212-2. Therefore, the specific effects of histamine and cannabinoids on SW756 migration and… CONTINUE READING
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