The influence of leukocyte filtration during cardiopulmonary bypass on postoperative lung function. A clinical study.

@article{Mihaljevi1995TheIO,
  title={The influence of leukocyte filtration during cardiopulmonary bypass on postoperative lung function. A clinical study.},
  author={Tomislav Mihaljevi{\'c} and Martin T{\"o}nz and Ludwig Karl von Segesser and Miralem Pasi{\'c} and Patricio Grob and J Fehr and Burkhard Seifert and Marko Ivan Turina},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1995},
  volume={109 6},
  pages={
          1138-45
        }
}
The accumulation of activated leukocytes in the pulmonary circulation plays an important role in the pathogenesis of lung dysfunction associated with cardiopulmonary bypass. Animal studies have demonstrated that the elimination of leukocytes from the circulation reduces postoperative lung injury and improves postoperative pulmonary function. We conducted a prospective randomized clinical study to evaluate whether postoperative lung function could be improved by use of a leukocyte filter during… CONTINUE READING