The influence of insulin on circulating ghrelin.

  title={The influence of insulin on circulating ghrelin.},
  author={Daniel E Flanagan and Mark Evans and Teresa P Monsod and Frances Rife and Rubina A. Heptulla and William V Tamborlane and Robert S. Sherwin},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={284 2},
Ghrelin is a novel peptide that acts on the growth hormone (GH) secretagogue receptor in the pituitary and hypothalamus. It may function as a third physiological regulator of GH secretion, along with GH-releasing hormone and somatostatin. In addition to the action of ghrelin on the GH axis, it appears to have a role in the determination of energy homeostasis. Although feeding suppresses ghrelin production and fasting stimulates ghrelin release, the underlying mechanisms controlling this process… CONTINUE READING
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