The influence of hyperinsulinaemia on calcium-phosphate metabolism in renal failure.

@article{Nowicki1998TheIO,
  title={The influence of hyperinsulinaemia on calcium-phosphate metabolism in renal failure.},
  author={Michał Nowicki and Franciszek Kokot and Andrzej Surdacki},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={1998},
  volume={13 10},
  pages={2566-71}
}
BACKGROUND Patients with renal failure are characterized by impaired insulin-mediated glucose uptake. Insulin plays a major role in the maintenance of phosphate homeostasis but it remains to be determined whether in uraemia insulin-dependent renal and extrarenal phosphate disposal is also affected. METHODS The effect of hyperinsulinaemia on serum concentrations of phosphate, ionized calcium and intact PTH as well as renal excretion of calcium and phosphate was studied under euglycaemic… CONTINUE READING