The influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area.

@article{Jacobson1981TheIO,
  title={The influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area.},
  author={Carol D. Jacobson and Valer J Csernus and J E Shryne and Roger A. Gorski},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1981},
  volume={1 10},
  pages={1142-7}
}
Although the volume of the sexually dimorphic nucleus of the preoptic area (SDN-POA) of the adult rat has been shown to be modified by the hormone environment early in postnatal life, the present study was performed to clarify several fundamental questions related to this process. This study was designed to evaluate the ability of exogenous testosterone propionate (TP), or a gonadal graft, to influence SDN-POA volume in rats which were gonadectomized as neonates. Orchidectomy on day 1 resulted… CONTINUE READING