The influence of genetic variations in HHEX gene on insulin metabolism in the German MESYBEPO cohort.

@article{Pivovarova2009TheIO,
  title={The influence of genetic variations in HHEX gene on insulin metabolism in the German MESYBEPO cohort.},
  author={Oksana Anatolyevna Pivovarova and Victoria J. Nikiforova and Andreas F. H. Pfeiffer and Natalia Rudovich},
  journal={Diabetes/metabolism research and reviews},
  year={2009},
  volume={25 2},
  pages={
          156-62
        }
}
BACKGROUND In the present study, we aimed to validate the type 2 diabetes (T2DM) susceptibility alleles identified in the first genome-wide association study in the hematopoietically expressed homeobox protein (HHEX) gene region (rs1111875 and rs7923837). Furthermore, we investigated quantitative metabolic risk phenotypes of these two variants for association with three key components of the insulin metabolism: insulin secretion, insulin sensitivity and insulin degradation. METHODS Two HHEX… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Similar Papers

Loading similar papers…