The influence of genetic variation in oxidative stress genes on human noise susceptibility

@article{Carlsson2005TheIO,
  title={The influence of genetic variation in oxidative stress genes on human noise susceptibility},
  author={Per-Inge Carlsson and Lut Van Laer and Erik Borg and Magdalena Bondeson and Guy Van Camp},
  journal={Hearing Research},
  year={2005},
  volume={202},
  pages={87-96}
}
Noise induced hearing loss (NIHL) is a complex disease caused by an interaction between genetic and environmental factors. Damage in the cochlea as a result of noise exposure appears to be mediated by reactive oxygen species (ROS). To investigate whether genetic variation in the human protective antioxidant system is associated with high or low susceptibility to NIHL, genetic polymorphisms derived from genes involved in the oxidative stress response were analysed in the 10% most susceptible and… CONTINUE READING
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