The influence of genetic background on conventional outflow facility in mice.

@article{BoussommierCalleja2013TheIO,
  title={The influence of genetic background on conventional outflow facility in mice.},
  author={Alexandra Boussommier-Calleja and Darryl R. Overby},
  journal={Investigative ophthalmology & visual science},
  year={2013},
  volume={54 13},
  pages={8251-8}
}
PURPOSE Intraocular pressure (IOP) varies between genetically distinct strains of mice. The purpose was to test the hypothesis that strain-dependent differences in IOP are attributable to differences in conventional outflow facility (C). METHODS The IOP was measured by rebound tonometry in conscious or anesthetized BALB/cJ, C57BL/6J, and CBA/J mice (N = 6-10 per strain). Conventional outflow facility was measured by ex vivo perfusion of enucleated eyes (N = 9-10 per strain). RESULTS… CONTINUE READING
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